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You can read a more in-depth explanation and analysis of risk from the Cleveland Clinic , but heres the bottom line: Out of an abundance of caution, anyone with a personal or family history making them more susceptible to C cell thyroid cancer (specifically) is advised not to use a GLP-1 medication

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In many cases, prescribers may determine that the risks outweigh the benefits, particularly if alternative treatments are available for either condition

This effect was even more pronounced in patients with resistant hypertension, where 26.9% decreased their blood pressure medication versus only 3% in the placebo group